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3D structures from the PDB for "Bifunctional dihydrofolate reductase-thymidylate synthase" AND "BDBM18512"
(Proteins have >= 85% sequence identity and ligands are exact matches)

Seq IdentityJmol DisplayPDB Title
1J3J100%JmolDOUBLE MUTANT (C59R+S108N) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP
3QGT100%JmolCRYSTAL STRUCTURE OF WILD-TYPE PFDHFR-TS COMPLEXED WITH NADPH, DUMP AND PYRIMETHAMINE
3UM5>99%JmolDOUBLE MUTANT (A16V+S108T) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS-T9/94) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP
3QG2>99%JmolPLASMODIUM FALCIPARUM DHFR-TS QRADRUPLE MUTANT (N51I+C59R+S108N+I164L, V1/S) PYRIMETHAMINE COMPLEX